{
  "$schema": "https://json-schema.org/draft/2020-12/schema",
  "$id": "schema:Gene",
  "title": "Gene",
  "description": "A discrete unit of inheritance which affects one or more biological traits (Source: [https://en.wikipedia.org/wiki/Gene](https://en.wikipedia.org/wiki/Gene)). Examples include FOXP2 (Forkhead box protein P2), SCARNA21 (small Cajal body-specific RNA 21), A- (agouti genotype).",
  "type": "object",
  "allOf": [
    {
      "description": "Any biological, chemical, or biochemical thing. For example: a protein; a gene; a chemical; a synthetic chemical.",
      "$ref": "schema:BioChemEntity"
    }
  ],
  "properties": {
    "alternativeOf": {
      "description": "Another gene which is a variation of this one.",
      "oneOf": [
        { "$ref": "schema:Gene" },
        { "type": "array", "items": { "$ref": "schema:Gene" } }
      ]
    },
    "encodesBioChemEntity": {
      "description": "Another BioChemEntity encoded by this one. ",
      "oneOf": [
        { "$ref": "schema:BioChemEntity" },
        { "type": "array", "items": { "$ref": "schema:BioChemEntity" } }
      ]
    },
    "expressedIn": {
      "description": "Tissue, organ, biological sample, etc in which activity of this gene has been observed experimentally. For example brain, digestive system.",
      "oneOf": [
        {
          "anyOf": [
            { "$ref": "schema:AnatomicalStructure" },
            { "$ref": "schema:AnatomicalSystem" },
            { "$ref": "schema:BioChemEntity" },
            { "$ref": "schema:DefinedTerm" }
          ]
        },
        {
          "type": "array",
          "items": {
            "anyOf": [
              { "$ref": "schema:AnatomicalStructure" },
              { "$ref": "schema:AnatomicalSystem" },
              { "$ref": "schema:BioChemEntity" },
              { "$ref": "schema:DefinedTerm" }
            ]
          }
        }
      ]
    },
    "hasBioPolymerSequence": {
      "description": "A symbolic representation of a BioChemEntity. For example, a nucleotide sequence of a Gene or an amino acid sequence of a Protein.",
      "oneOf": [
        { "type": "string" },
        { "type": "array", "items": { "type": "string" } }
      ]
    }
  }
}